Gender-Specific Response in Pain and Function to Biologic Treatment of Knee Osteoarthritis: A Gender-Bias-Mitigated, Observational, Intention-to-Treat Study at Two Years

Table 5

Gender-specific improvement at two-year follow-up after gender bias mitigation by randomized undersampling.

Measure	Outcome	Gender	Difference of the means	95% credible interval of the difference of the means
VAS	Pain reduction (−)	Women	-28.8	-34.4 to -23.6
		Men	-9.7	-16.0 to -3.0
OKS	Function improvement (+)	Women	+12.2	+10.3 to +14.1
		Men	+4.6	+2.5 to +6.8

Source: authors’ data and reproducible statistical analysis with Open Access statistical software R (version 4.0.0 or higher).