Age-Related Macular Degeneration (AMD) Transmitochondrial Cybrids Protected from Cellular Damage and Death by Human Retinal Progenitor Cells (hRPCs)

<div>System design. (a) A schematic of the process for creating AMD and normal cybrids using polyethylene glycol fusion of mitochondria-free ARPE-19 (Rho0) cells and mitochondria-rich platelets isolated from peripheral blood of AMD patients or age-matched normal patients. (b) A schematic which illustrates the bidirectional signaling pathway mediated by the coculture of hRPCs with AMD cybrids. (c) A schematic of the process for isolating human retinal progenitor cells from human fetal eyes. <sup>a</sup>Human fetal eyes (17-20 weeks gestational age) were obtained from the therapeutic termination of pregnancy.</div>

Stem Cells International

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Figure 1: Age-Related Macular Degeneration (AMD) Transmitochondrial Cybrids Protected from Cellular Damage and Death by Human Retinal Progenitor Cells (hRPCs) 

Figure 1 | Age-Related Macular Degeneration (AMD) Transmitochondrial Cybrids Protected from Cellular Damage and Death by Human Retinal Progenitor Cells (hRPCs) 