Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects

<div>Antiapoptotic effect of primed MSCs. (a) Images of serum-starved H4SW cells cocultured with naïve MSCs or primed MSCs for 24 h. Scale bar: 40 <i>μ</i>m. (b) The number of viable cells in different experimental groups was counted by the trypan blue staining method. (c) Western blot analysis of cell death markers, cleaved PARP, and cleaved caspase-3. (d) The densitometry results are presented as fold change compared to H4SW cells. The data were normalized to <i>β</i>-actin expression. 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Stem Cells International

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Figure 2

Figure 2: Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects 