Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects

<div>Identification of SGRN as a secretory protein of H4SW cells. The gene expression patterns of H4SW cells were upregulated compared to H4 cells. (a) Scatter plot and (b) Euclidean distance clustering of significant genes performed by MeV software are presented as log-transformed data. The green and red colors indicate decreased and increased gene expression, respectively. (c) ELISA assay of SRGN concentrations in H4 and H4SW cell cultures. Three samples per experimental group were tested in each assay. 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Stem Cells International

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Figure 7

Figure 7: Exposure of Mesenchymal Stem Cells to an Alzheimer’s Disease Environment Enhances Therapeutic Effects 