HGF-Modified Dental Pulp Stem Cells Mitigate the Inflammatory and Fibrotic Responses in Paraquat-Induced Acute Respiratory Distress Syndrome

Figure 2

DPSCs alleviate the inflammatory responses of BEAS-2B and MRC-5 cells better than UC-MSCs. (a) The expression of inflammatory cytokines, including TNF-α, IL-1β, IL-6, IL-8, IL-4, IL-10, and IL-13, in BEAS-2B cells was evaluated by qPCR. (b) The expression of inflammatory cytokines, including IL-6, IL-10, and IL-13, in MRC-5 cells was measured by qPCR. Each experiment was performed in triplicate. The data are shown as the . ANOVA followed by Tukey’s multiple comparisons test was used to evaluate these data. ^### and ^#### vs. Con; , , , and vs. the TGF-β group; ^&, ^&&, ^&&&, and ^&&&& vs. UC-MSCs. Con: control; UC-MSCs: umbilical cord mesenchymal stem cells; DPSCs: dental pulp mesenchymal stem cells.

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