Research Article
Intranasally Administered Extracellular Vesicles from Adipose Stem Cells Have Immunomodulatory Effects in a Mouse Model of Asthma
Figure 1
The experimental protocol. (a) Mice were sensitized on days 0, 1, 7, and 8 by intraperitoneal injection of ovalbumin (OVA) and then challenged intranasally with OVA on days 14, 15, 21, and 22. On days 12, 13, 19, and 20, 10 μg/50 μl of the adipose stem cell- (ASC-) derived extracellular vesicles (EVs) was administered intranasally. (b) Mice were divided into 4 groups according to different sensitization, challenge, and pretreatment methods.
(a) |
(b) |