Intranasally Administered Extracellular Vesicles from Adipose Stem Cells Have Immunomodulatory Effects in a Mouse Model of Asthma

Figure 7

Effects of adipose stem cell- (ASC-) derived extracellular vesicles (EVs) on T cell populations in the lung draining lymph nodes. The populations of CD4⁺CD25⁺Foxp3⁺ T cells were markedly increased by administration of ASC-derived EVs in the OVA group. ASC-derived EV administration significantly reduced CD4⁺IL-4⁺ T cells but promoted CD4⁺IFN-γ⁺ T cells.