Melatonin Alleviates LPS-Induced Pyroptotic Cell Death in Human Stem Cell-Derived Cardiomyocytes by Activating Autophagy

<div>Experimental timeline and cell culture. (a) Flow chart of experiments. (b) Bright-field images of cultured hiPSCs. Scale bars: 200 <i>μ</i>m. (c) Bright-field images of beating cardiomyocytes on day 9 and purified cardiomyocytes on day 13. Scale bars: 200 <i>μ</i>m. (d) Bright-field images of purified and reinoculated hiPSC-CMs. Scale bars: 200 <i>μ</i>m.</div>

Stem Cells International

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Figure 1

Figure 1: Melatonin Alleviates LPS-Induced Pyroptotic Cell Death in Human Stem Cell-Derived Cardiomyocytes by Activating Autophagy 