Research Article
Melatonin Alleviates LPS-Induced Pyroptotic Cell Death in Human Stem Cell-Derived Cardiomyocytes by Activating Autophagy
Figure 6
Melatonin attenuates pyroptosis in LPS-exposed hiPSC-CMs via enhancing autophagy. (a) Representative images of flow cytometry results. (b) Quantitative analysis of pyroptosis rate. (c) Measurement of LDH release level. (d) Supernatant IL-1β level examined by the ELISA assay. (e) Supernatant IL-18 level examined by the ELISA assay. Mel was administered at 10 μmol/l. ; vs. control; vs. control; # vs. LPS; ## vs. LPS.
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