The Influence of the Surface Topographical Cues of Biomaterials on Nerve Cells in Peripheral Nerve Regeneration: A Review

Table 1

Summary of the influence of topographical features on the proliferation and differentiation of cells.

Feature type	Cell type	Effects on cell behaviors	Reference
PLA nanofiber stents	Neurons and glial cells	Promote neuron and glial cell growth	[32]
Mussel protein glue-based nanofiber conduit	Nerve and Schwann cells	Promote nerve and Schwann cell proliferation and differentiation	[33]
Nanotextured glass coverslips	PC12 cell	Promote the proliferation of neuronal cells and provide treatment for central nervous system trauma	[35]
A customizable multilevel architecture array	Neurons	Enhance the differentiation of neurons	[36]
The engineered concave microarray	Cardiomyocytes and neurons	The differentiation of cardiomyocytes and neurons	[37]
Polycaprolactone/polyethylene oxide–polycaprolactone-blended fiber materials using electrospinning technology	Neural stem cells	Promotes the growth of rat neural stem cells, differentiates into neurons and astrocytes	[38]