Review Article
Strategies to Improve the Quality and Freshness of Human Bone Marrow-Derived Mesenchymal Stem Cells for Neurological Diseases
Table 1
Genes related to the transcriptomic network of the quality and freshness of starved human bone marrow-derived mesenchymal stem cells (hBM-MSCs).
| Entrez gene name | Symbol | Affymetrix ID | Location | Signal (fold change)a | 6 h | 12 h |
| Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | PIK3CG | 206370_at | Cytoplasm | -11.70 | -22.42 | erbb2 interacting protein | ERBIN | 232896_at | Cytoplasm | -1.10 | -19.71 | Solute carrier family 25 member 27 | SLC25A27 | 230624_at | Cytoplasm | -9.20 | -12.39 | BCL2 apoptosis regulator | BCL2 | 207005_s_at | Cytoplasm | -7.73 | -9.99 | Peroxiredoxin 3 | PRDX3 | 209766_at | Cytoplasm | 1.85 | -9.27 | NADPH oxidase 5 | NOX5 | 1553023_a_at | Cytoplasm | 1.70 | 11.82 | Neutrophil cytosolic factor 4 | NCF4 | 205147_x_at | Cytoplasm | -1.19 | 12.5 | Protein kinase AMP-activated catalytic subunit alpha 2 | PRKAA2 | 238441_at | Cytoplasm | 12.61 | 22.26 | Phosphatase and tensin homolog | PTEN | 242622_x_at | Cytoplasm | 3.62 | 54.26 | Angiotensinogen | AGT | 202834_at | Extracellular Space | 1.04 | -27.13 | TNF superfamily member 14 | TNFSF14 | 233935_at | Extracellular Space | -1.19 | -23.12 | Albumin | ALB | 211298_s_at | Extracellular Space | 8.07 | -20.19 | Alpha-microglobulin/bikunin precursor | AMBP | 214425_at | Extracellular Space | -4.55 | -10.51 | Adiponectin, C1Q, and collagen domain containing | ADIPOQ | 207175_at | Extracellular Space | -3.15 | -10.1 | Serpin family B member 5 | SERPINB5 | 1555551_at | Extracellular Space | 6.58 | 10.19 | Insulin-like growth factor 1 | IGF1 | 209542_x_at | Extracellular Space | 8.20 | 17.32 | von Hippel-Lindau tumor suppressor | VHL | 203844_at | Nucleus | -1.33 | -37.9 | MacroH2A.1 histone | MACROH2A1 | 1558779_at | Nucleus | 1.76 | 12.75 | Integrin subunit beta 1 | ITGB1 | 215878_at | Plasma Membrane | 12.40 | -36.23 | Fibroblast growth factor receptor 2 | FGFR2 | 211400_at | Plasma Membrane | 4.66 | -15.37 | Low-density lipoprotein receptor | LDLR | 217103_at | Plasma Membrane | -12.50 | -11.9 | Glutamate metabotropic receptor 5 | GRM5 | 207235_s_at | Plasma Membrane | -10.02 | -10.17 | CD36 molecule | CD36 | 242197_x_at | Plasma Membrane | 3.27 | -9.46 | Presenilin 1 | PSEN1 | 1559206_at | Plasma Membrane | -2.64 | 9.57 | Fc fragment of IgG receptor IIa | FCGR2A | 203561_at | Plasma Membrane | 13.11 | 13.69 | Toll-like receptor 7 | TLR7 | 220146_at | Plasma Membrane | 2.10 | 24.72 | Prostaglandin E receptor 3 | PTGER3 | 210375_at | Plasma Membrane | -17.22 | 27.73 |
|
|
aNormalized ratio of fold change of the signal at 6 and 12 h of storage, relative to the corresponding signal of the control group.
|