Advances in Female Germ Cell Induction from Pluripotent Stem Cells

Figure 1

Schematic of female germ cell development and key gene expressions during the development. Developmental timelines and stages of mouse and human female germ cell development are shown in the center. PGCs undergo specification and migration then arrive at the genital ridge. After sex differentiation, PGCs subsequently undertake RA responsive phase, meiosis initiation, and oocyte development. Key gene expressions corresponding to different developmental stages are shown in yellow bars.