Inhibition of Notch Signaling Promotes the Differentiation of Epicardial Progenitor Cells into Adipocytes

Figure 2

EPCs migrated out from the edge of embryonic mouse heart. (a) The cobblestone-like EPCs grew from the edge of the embryonic ventricular tissue after 24 hours’ culture. (b) The cobblestone-like EPCs continued growing from the edge of the embryonic ventricular tissue after 48 hours’ culture. (c) Cobblestone-like EPCs were observed after removing the ventricular tissue. (d, e) Immunofluorescence staining showed all cultured EPCs expressed Tbx18 and Wt1.

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