Review Article

Myogenic Differentiation of Stem Cells for Skeletal Muscle Regeneration

Table 2

Stem cells in myogenic differentiation.

Stem cell typesStem cell sourcesMarkersAdvantages

Satellite cellsMuscle biopsyHEYL, KLF4, MYOD, PAX7, Myf5, CD82Direct precursor of skeletal muscle
Mesenchymal stem cellsBone marrow biopsy (BMSC), adipose tissue (ADSC), and other mesenchymal tissuesCD73, CD90, CD105 and lacking CD11b, CD14, CD19, CD34, CD45, CD79aEasy to obtain and low carcinogenic risk
Induced pluripotent stem cellsAlmost every adult tissueKLF4, c-MYC, OCT4, SOX2Pluripotent differentiation potential and high differentiation efficiency