Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem Cells

<div>Effect of Chaetocin on MSC osteogenic differentiation. (a, b) Real-time RT-PCR analysis shows that expression of both early and later osteogenic markers (Runx2, OPN) was significantly enhanced by treatment with Chaetocin. (c, d) ALP staining showed a significant increase of ALP activity in MSCs treated with Chaetocin. (e, f) ARS staining showed a significant increase of calcium deposition in MSCs treated with Chaetocin. 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Stem Cells International

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Figure 1

Figure 1: Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem Cells 