Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem Cells

<div>Treatment of Chaetocin increase Wnt/<i>β</i>-catenin activities. (a) Western blot shows nuclear <i>β</i>-catenin protein levels were elevated by Chaetocin treatment in MSC culture at day 7. Histone H1 was used as a loading control. (b) Real-time RT-PCR analysis shows that Wnt/<i>β</i>-catenin target genes (Cnnd1, Axin2, Myc, and Dkk1) were significantly increased by treatment with Chaetocin. 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Stem Cells International

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Figure 3

Figure 3: Chaetocin Promotes Osteogenic Differentiation via Modulating Wnt/Beta-Catenin Signaling in Mesenchymal Stem Cells 