To Breathe or Not to Breathe: The Role of Oxygen in Bone Marrow-Derived Mesenchymal Stromal Cell Senescence

Table 1

Summary of studies investigating the effects of hypoxia on BMSC senescence.

Study findings	References
Proliferation and cellular metabolism of hypoxic human BMSCs	[47, 50, 53, 56, 58, 63, 67, 82–84]
Proliferation and osteogenic capacity of hypoxic rat BMSCs	[103]
Osteogenic differentiation of hypoxic human BMSCs	[49, 55, 56, 58, 61, 63, 82, 104, 106, 107]
Adipogenic differentiation of hypoxic human BMSCs	[56, 58, 60, 61, 63, 82, 107]
Chondrogenic capacity of hypoxic human BMSCs	[63, 82, 107]
Chondrogenic capacity of hypoxic rat BMSCs	[57]
Autophagy in hypoxic human BMSCs	[94]