Research Article
Sox9-Increased miR-322-5p Facilitates BMP2-Induced Chondrogenic Differentiation by Targeting Smad7 in Mesenchymal Stem Cells
Figure 6
BMP2-induced chondrogenesis was enhanced by miR-322-5p. (a–d) WB revealed that overexpression of miR-322-5p inhibited expression of Smad7 and COL10A1 and promoted that of COL2A1; silencing of miR-322-5p brought the opposite changes. (e–g) Results of qPCR mimicked those of WB. (h) Alcian Blue staining supported the effect of miR-322-5p in facilitating BMP2-induced chondrogenesis. , , and . B2: BMP2; S9: Sox9; shS9: shSox9.
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