Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway

<div>miR-21 regulates HCECs’ proliferation and migration by activating PI3K/Akt pathway through targeting PTEN. (a, d) HUMSC-sEV treatment decreased the RNA and protein levels of PTEN in HCECs. (b) The expression level of miR-21 in HCECs. (c, f) The PTEN changed with miR-21 variation. (e) The expression of phospho-Akt after overexpression of PTEN. (g) The expression level of phospho-Akt after transfected with miR-21 mimics was detected by Western blot. 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Stem Cells International

fig6

Figure 6

Figure 6: Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway 

Figure 6 | Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway 