Research Article

Researches on Stem and Progenitor Cells in Intervertebral Discs: An Analysis of the Scientific Landscape

Table 4

Details of top 9 clusters for researches on stem and progenitor cells in intervertebral discs.

Cluster no.Size ()SilhouetteMean (year)LSILLRMI

0650.6052011Mesenchymal stem cell; intervertebral disc; stem cell; intervertebral disc degeneration; nucleus pulposus | nucleus pulposus cell; disc cell; mesenchymal stem; disc degeneration; disc regenerationHuman intervertebral disc; skeletal progenitor cell; human cartilage endplate; human nucleus; potential stem cell nichesPhenotypic marker; human degenerative intervertebral disc; iron oxide; cell survival; hypoxic-preconditioned bone
1640.6652012Mesenchymal stem cell; adipose-derived stem cell; nucleus pulposus; nucleus pulposus cell; intervertebral disc | marrow-derived mesenchymal stem cell; rabbit model; signaling pathway; pulposus-like differentiation; collagen-induced nucleusAdipose-derived mesenchymal stem cell; adipose-derived stem cell; co-culture system; nucleus pulposus; pulposus-like cellPhenotypic marker; human degenerative intervertebral disc; iron oxide; cell survival; hypoxic-preconditioned bone
2560.8172011Mesenchymal stem cell; intervertebral disc degeneration; nucleus pulposus cell; intervertebral disc; stem cell | nucleus pulposus; human cartilage; progenitor cell; adipose-derived stem cell; pulposus-derived mesenchymal stem cellIntervertebral disc degeneration; nutrition deficiency; autologous hematopoietic progenitor cell support; high-dose chemotherapy; optic discPhenotypic marker; human degenerative intervertebral disc; iron oxide; cell survival; hypoxic-preconditioned bone
3520.7472009Mesenchymal stem cell; intervertebral disc; nucleus pulposus cell; human mesenchymal stem cell; degenerative disc model | intervertebral disc degeneration; nucleus pulposus; rabbit model; bone marrow; adipose-derived stem cellDegenerative disc model; disc regeneration; canine disc degeneration model; disc cell; AKT axisPhenotypic marker; human degenerative intervertebral disc; iron oxide; cell survival; hypoxic-preconditioned bone
4490.7182016Mesenchymal stem cell; intervertebral disc; nucleus pulposus; stem cell; intervertebral disc degeneration | progenitor cell; regenerative medicine; articular cartilage; enhanced regenerative effect; adipose stemNucleus pulposus regeneration; annulus fibrosus regeneration; pulposus-based cell delivery system; cyclic compression; perfusion bioreactorCell survival; hypoxic-preconditioned bone; phenotypic marker; human degenerative intervertebral disc; iron oxide
5430.7352014Mesenchymal stem cell; intervertebral disc; human cartilage; endplate-derived stem cell; splicing event | nucleus pulposus progenitor cell; mesenchymal stem cell differentiation; disc cell; collagen type ii; hypoxic conditionHuman cartilage; endplate-derived stem cell; splicing event; genome-wide analysis; stromal cellHuman degenerative intervertebral disc; phenotypic marker; iron oxide; cell survival; hypoxic-preconditioned bone
6370.7252011Mesenchymal stem cell; nucleus pulposus cell; human mesenchymal stem cell; vitro study; pulposus-like cell | adipose stem cell; configuration effect; co-cultured stem cell; matrix production; low back pain patient3d culture; alginate beads hypoxia bone; synthetic peptide b2a; modeling nucleus; vitro studyPhenotypic marker; human degenerative intervertebral disc; iron oxide; cell survival; hypoxic-preconditioned bone
7370.6812013Mesenchymal stem cell; nucleus pulposus; scaffold-free cartilage-like disc-shaped cell sheet; shrinkage-free preparation; using human bone marrow | intervertebral disc degeneration; human mesenchymal stem cell; pentosan polysulfate; ovine model; mesenchymal progenitor cellShrinkage-free preparation; scaffold-free cartilage-like disc-shaped cell sheet; using human bone marrow; human placenta-derived mesenchymal stem cell; functional regenerationPhenotypic marker; human degenerative intervertebral disc; iron oxide; cell survival; hypoxic-preconditioned bone
8270.8872005Polylactide disc; temporomandibular joint disc; mesenchymal stem cell; intervertebral disc; tissue engineering | nucleus pulposus; bone marrow stem cell; differential response; chitosan hydrogel; iron oxidePolylactide disc; temporomandibular joint disc; bone marrow formation; tissue engineering; leukocyte cell adhesion moleculeMesenchymal stem cell; intervertebral disc; nucleus pulposus cell; iron oxide; phenotypic marker