Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation-Related Tumorigenesis via Modulating Macrophages

<div>HUC-MSCs regulate inflammatory cytokine production in colitis and colitis-related colon cancer. (a–c) HUC-MSC treatment reduced TNF-<i>α</i> and IL-6 while increased TGF-<i>β</i>1 in the serum of AOM/DSS-treated mice. (d, e) HUC-MSC treatment reduced proinflammatory cytokines produced by macrophages in serum caused by DSS. (f, g) HUC-MSC treatment reduced IFN-<i>γ</i> and IL-4 in serum of colitis mice. (h, i) HUC-MSC treatment reduced IL-17 while increased TGF-<i>β</i>1 in serum caused by DSS. 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Stem Cells International

fig5

Figure 5

Figure 5: Umbilical Cord Mesenchymal Stem Cells Ameliorate Inflammation-Related Tumorigenesis via Modulating Macrophages 