Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells

<div>CLA treatment inhibited in vitro migration of HCC cell lines. (a), (b), (d) Scratch assay analysis showed that CLA treatment (Sk-Hep-1: 60 <i>μ</i>M, Hep-3B: 100 <i>μ</i>M) reduced the migration velocity of both HCC cell lines with or without mitomycin C treatment as compared to the control groups. However, BIM treated groups (Sk-Hep-1: 780 nM, Hep-3B: 1170 nM) showed enhanced motility in both experimental groups. (c), (e) The scratched areas that remained vacant were larger in CLA treated groups in comparison with control groups in both cell lines. BIM treatment in both cell lines resulted in an enhanced motility of cells and covering of almost all scratched areas. 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Stem Cells International

fig3

Figure 3

Figure 3: Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells 