Research Article

Conjugated Linoleic Acid Treatment Attenuates Cancerous features in Hepatocellular Carcinoma Cells

Figure 4

HNF4α induction resulted in improved hepatocytic differentiation of Hep-3B cells after CLA treatment. (a) Immunofluorescence staining revealed the remarkable expression of ALB in the CLA treated Hep-3B cells compared to the BIM treated and control group. (b) CLA treatment increased ALB secretion from Hep-3Bcells. (c) The relative mRNA expression of the ALB gene was increased after treatment with CLA in Hep-3B cells compared to the control group. (d) PAS staining showed glycogen accumulation in CLA treated cells as compared to BIM treated group. PAS: periodic acid-Schiff staining. Data are presented as the , ( and ).
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