Mesenchymal Stem Cells Alleviate Renal Fibrosis and Inhibit Autophagy via Exosome Transfer of miRNA-122a

<div>Differentially expressed miRNA profiles between TGF-<i>β</i>1-treated HK-2 cells treated with mesenchymal stem cell (MSC) supernatant+GW4869 and MSC-exo. (a) The length distribution of identified miRNAs. (b) The miRNA nucleotide bias at each position. (c) The overall distribution of the expression of each sample. (d) Volcano plot of the identified miRNAs. (e) Hierarchical clustering analysis of differentially expressed miRNAs.</div>

Stem Cells International

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Figure 2: Mesenchymal Stem Cells Alleviate Renal Fibrosis and Inhibit Autophagy via Exosome Transfer of miRNA-122a 