FAIM Enhances the Efficacy of Mesenchymal Stem Cell Transplantation by Inhibiting JNK-Induced c-FLIP Ubiquitination and Degradation

Figure 7

Graphical abstract: Schematic diagram of the proposed mechanism; schematic diagram of the proposed mechanisms by which FAIM impairs the JNK-mediated, ubiquitination–proteasome-dependent degradation of c-FLIP, thereby effectively promoting MSC survival and ultimately ameliorating cardiac function and improving the prognosis of MI in vivo.