[Retracted] lncRNA DARS-AS1 Modulates TSPAN1-Mediated ITGA2 Hypomethylation by Interaction with miR-194-5p Thus Promoting Ovarian Cancer Progression

Figure 4

miR-194-5p leads to a targeted inhibition of TSPAN1 and regulates OC cell behaviors by targeting TSPAN1. (a) Database analysis and luciferase activity assays showing targeted inhibition of TSPAN1 by miR-194-5p. (b) GEPIA 2 database analysis, qRT-PCR detection, and western blotting analysis showing TSPAN1 is upregulated in OC. (c) qRT-PCR detection and western blotting of TSPAN1 expressions in A2780 cells following transfection with si-TSPAN1 and/or miR-194-5p inhibitor. (d) CCK-8 assay detection of A2780 cell viability following transfection with si-TSPAN1 and/or miR-194-5p inhibitor. (e) Representative migratory or invasive A2780 cells per field and numbers of migratory or invasive cells following transfection with si-TSPAN1 and/or miR-194-5p inhibitor. (f) Apoptosis rates of A2780 cells, western blots, and gray values of apoptosis-related proteins in A2780 cells following transfection with si-TSPAN1 and/or miR-194-5p inhibitor. A symbol of represents .

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