Research Article
Force-Induced Nitric Oxide Promotes Osteogenic Activity during Orthodontic Tooth Movement in Mice
Figure 5
Force-induced NO in PDLSCs may be regulated by iNOS via the PI3K/Akt signal pathway. (a) Western blot indicating that PI3K P85α, p-Akt, and active β-catenin levels were significantly increased after 12 h CTF. (b) While PI3K inhibitor LY294002 reduced the upregulation of these markers. (c) The NO inhibitor L-NMMA also suppressed the upregulation of the PI3K/Akt pathway treated by CTF.
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