The Effect of Human Bone Marrow Mesenchymal Stem Cell-Derived Exosomes on Cartilage Repair in Rabbits

Figure 3

hBMSC-EXOs promote cell migration and mitochondrial function in chondrocytes. Rabbit primary chondrocytes were treated with hBMSC-EXOs at for 24 h or 48 h. Cell migration and mitochondrial membrane potential were assayed. (a) hBMSC-EXOs stimulate cell migration. Wound healing assay was used to evaluate cell migration. . (b) Quantitative data for wound healing assay as shown in (a). (c) hBMSC-EXOs increase the mitochondrial membrane potential. Representative fluorescence images for JC-1 staining were shown. . (d) Quantitative analysis for JC-1 staining as shown in (c). . Values are presented as . , , and , versus the control group, one-way ANOVA.

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