Serial Gene Expression Profiling of Neural Stem Cells Shows Transcriptome Switch by Long-Term Physioxia from Metabolic Adaption to Cell Signaling Profile

Table 3

Affected pathways from upregulated genes in midbrain and cortex NSCs cultivated for 13 days in physioxia.

	Midbrain NSCs				Cortical NSCs
	Number of genes	Fold enrichment	P value		Number of genes	Fold enrichment	P value
PANTHER pathways Mus musculus (reference)				PANTHER pathways Mus musculus (reference)
—				Amino acid transport across the plasma membrane	4	28.63	2.86E-02
Reactome pathways Mus musculus (reference)				Reactome pathways Mus musculus (reference)
Regulation of IGF transport and uptake by IGF binding proteins	10	8.25	1.25E-03	—
Post-translational protein phosphorylation	9	7.82	6.76E-03