Implantation of Hypoxia-Induced Mesenchymal Stem Cell Advances Therapeutic Angiogenesis

Figure 8

In vitro cell migration assays of mesenchymal stem cells (MSCs), hypoxia-induced MSCs (hi-MSCs), coculture of MSCs with human umbilical vein endothelial cells (HUVECs) (MSC coculture), and coculture of hi-MSCs with HUVECs (hi-MSC coculture) at each time point of the 3^rd hour (3 hr), 6^th hour (6 hr), and 10^th hour (10 hr) with (a, c) 3 μm pore-sized inserts and (b, d) 8 μm pore-sized. The hi-MSC population of cells may have added potential for coculture migration capacity compared to the MSC population of cells. Scale bar: 50 μm.

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