Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats

Table 2

Quantitative analysis of vascular function after treatment with bone marrow culture-derived conditioned medium (CM) against ischemia/reperfusion (IR) injury in aortic rings obtained from (a) nondiabetic control and (b) diabetic rats.

(a)

	Control; (-32, 8 rats)	Control-IR; (-31, 8 rats)	Control-IR+CM; (, 10 rats)
PE (g)
PE (% of KCl)
pD2 to PE
KCl (g)
to ACh (%) (5x10^-6M)
pD2 to ACh
to SNP (%)(5x10^-7M)
pD2 to SNP

(b)

	DM; (-32, 8 rats)	DM-IR; (-44, 10-11 rats)	DM-IR+CM; (-44, 11 rats)
PE (g)
PE (% of KCl)
pD2 to PE
KCl (g)
to ACh (%)
pD2 to ACh
to SNP (%)(5x10^-7M)
pD2 to SNP

Data are represented as the . PE: phenylephrine; KCl: potassium chloride; ACh: acetylcholine; SNP: sodium nitroprusside; : maximum relation; pD₂: negative logarithm of the corresponding half-maximum response (EC₅₀). Data were represented as mean SEM. versus corresponding control or DM; ^# versus corresponding control-IR or DM-IR.