Human Bone Marrow Mesenchymal Stem Cell (hBMSCs)-Derived miR-29a-3p-Containing Exosomes Impede Laryngocarcinoma Cell Malignant Phenotypes by Inhibiting PTEN

<div>HBMSC-derived Exo with upregulated miR-29a-3p inhibited laryngocarcinoma cell malignant progression. (a) QRT-PCR analysis of miR-29a-3p in hBMSC-derived Exo, M4E, and Hep2 cells. (b) QRT-PCR analysis of miR-29a-3p in hBMSC-derived Exo after the transfection of miR mimics and miR-NC. (c–f) The Exo derived from miR mimics or miR-NC-transfected hBMSCs were used to stimulate M4E and Hep2 cells for 48 h. (c) CCK-8 assay. (d) Colony formation assay. (e) Transwell assay for detecting cell invasive and migratory rates. (f) Flow cytometry analysis of apoptotic rate. 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Stem Cells International

fig5

Figure 5

Figure 5: Human Bone Marrow Mesenchymal Stem Cell (hBMSCs)-Derived miR-29a-3p-Containing Exosomes Impede Laryngocarcinoma Cell Malignant Phenotypes by Inhibiting PTEN 

Figure 5 | Human Bone Marrow Mesenchymal Stem Cell (hBMSCs)-Derived miR-29a-3p-Containing Exosomes Impede Laryngocarcinoma Cell Malignant Phenotypes by Inhibiting PTEN 