Research Article

Human Bone Marrow Mesenchymal Stem Cell (hBMSCs)-Derived miR-29a-3p-Containing Exosomes Impede Laryngocarcinoma Cell Malignant Phenotypes by Inhibiting PTEN

Figure 6

The impacts of Exo miR-29a-3p inhibitor and Exo si-PTEN in laryngocarcinoma cell progression. (a–b) MiR-29a-3p inhibitor and si-PTEN were transfected into hBMSCs, and the Exo was isolated. QRT-PCR analysis of the levels of miR-29a-3p (a) and PTEN (b). (c–f) The Exo derived from inhibitor NC, miR inhibitor, si-PTEN, or miR inhibitor + si-PTEN transfected hBMSCs were used to stimulate M4E and Hep2 cells for 48 h. (c) CCK-8 assay. (d) Colony formation assay. (e) Transwell assay for detecting cell invasive and migratory rates. , , and .
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