Mesenchymal Stem Cells (MSCs): A Novel Therapy for Type 2 Diabetes

Figure 3

Structures and the mathematical equations of the available PK model of MSCs. (a) Schematic diagram of the PK model for the administered MSCs in vivo. Solid arrows indicate the blood flow, dashed grey arrows indicate the depletion of MSCs, and grey boxes indicate the arrested MSCs isolated from blood circulation as in the extravascular space of the organ. (b) The equations to calculate MSC concentration in the respective organs [79].