Cell sources Year Team Journal Results Reference BMSCs 2003 Angele et al. J Orthop Res Cyclic hydrostatic pressure promoted chondrogenic differentiation of BMSCs. [159 ] 2004 Angele et al. Biorheology Cyclic compressive loading promoted chondrogenic differentiation of BMSCs. [150 ] 2004 Huang et al. Stem Cells Cyclic compressive loading (1 Hz, 10% magnitude) promoted chondrogenic differentiation of BMSCs [152 ] 2005 Huang et al. Stem Cells Cyclic compressive loading (1 Hz, 15% magnitude) promoted chondrogenic differentiation of BMSCs. [151 ] 2006 Miyanishi et al. Tissue Eng Different levels of cyclic hydrostatic pressure (1 Hz, 0.1, 1, and 10 MPa) differentially regulated BMSC chondrogenesis in the presence of TGF-β 3. [160 ] 2007 Mouw et al. Stem Cells Cyclic compressive loading (1 Hz, [153 ] 2010 Li et al. Tissue Eng Part A Cyclic compressive loading combined with surface shear force promoted the chondrogenic differentiation of BMSCs. [157 ] 2010 Li et al. J Cell Mol Med Cyclic compressive loading combined with surface shear stress promoted the chondrogenic differentiation of BMSCs. [158 ] 2010 Connelly et al. Tissue Eng Part A Cyclic tensile loading (1 Hz, 10% magnitude) specifically promoted the synthesis of collagen-I by BMSCs. [164 ] 2011 Baker et al. Tissue Eng Part A Cyclic tensile loading (1 Hz, 3% magnitude) promoted ECM synthesis by BMSCs. [165 ] 2018 Gan et al. Stem Cells Int Compared with no-compression controls, low-magnitude dynamic compressive loading (5%, 1 Hz) promoted ECM synthesis without affecting BMSC viability, whereas high-magnitude dynamic compressive loading (10% and 20%, 1 Hz) inhibited their viability and ECM synthesis. [154 ] 2022 Cheng et al. Tissue Eng Regen Med Hydrostatic pressure promoted chondrogenic differentiation of BMSCs cocultured with RPF. [163 ] AD-MSCs 2009 Ogawa et al. Tissue Eng Part A Cyclic hydrostatic pressure (0.5 Hz, 0-0.5 MPa) promoted the chondrogenic differentiation of AD-MSCs. [161 ] 2014 Dai et al. J Biomech Dynamic compression of intermittent dynamic hydrostatic pressure promoted the proliferation of AD-MSCs and induces their differentiation into NP-like cells. [162 ] 2015 Zhang et al. Eur Rev Med Pharmacol Sci Cyclic compressive loading combined with exogenous sox-9 promoted the proliferation and chondrogenic differentiation of AD-MSCs. [155 ] 2021 Abusharkh et al. In Vitro Cell Dev Biol Anim High cyclic tensile loading (10% magnitude) promoted ECM synthesis without affecting the viability of AD-MSCs. [166 ] NP-MSCs 2018 Liang et al. Stem Cells Int Compressive loading (1 MPa) inhibited NP-MSC viability, migration, and expression of stemness genes (Sox-2 and Oct4). [156 ] 2021 He et al. Autophagy Hydrostatic pressure (1.0 MPa) inhibited NP-MSC viability. [92 ]
