Small Extracellular Vesicles from Inflamed Adipose Derived Stromal Cells Enhance the NF-<i>κ</i>B-Dependent Inflammatory/Catabolic Environment of Osteoarthritis

<div>Experimental outline of the research work undertaken in the paper: sEVs_IL-1 collection from IL-1 treated ADSC; purification of sEVs_IL-1 through a combined precipitation and size exclusion chromatography method; addition of sEVs_IL-1 to primary cultures of chondrocytes and synoviocytes; analysis of the effects at the gene and protein level and molecular hypothesis underlying the observed effects.</div>

Stem Cells International

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Figure 9: Small Extracellular Vesicles from Inflamed Adipose Derived Stromal Cells Enhance the NF-<i>κ</i>B-Dependent Inflammatory/Catabolic Environment of Osteoarthritis 

Figure 9 | Small Extracellular Vesicles from Inflamed Adipose Derived Stromal Cells Enhance the NF-κB-Dependent Inflammatory/Catabolic Environment of Osteoarthritis 