Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment

<div>EPO moderated apoptosis and angiogenesis of PDLSCs through targeting autophagy under inflammatory microenvironment. (a, b) mRNA and protein expression levels of VEGF-a, FGF-2, IGF-1, Bax/Bcl2, Beclin1, and LC3B through qPCR and western blot. (c) Tube formation under different treatments. (d) Cell apoptosis rate under different treatments. (e, f) Immunofluorescence on DAPI, cytoskeleton, and VEGF-a/LC3B. 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Stem Cells International

fig7

Figure 7

Figure 7: Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment 

Figure 7 | Erythropoietin Activates Autophagy to Regulate Apoptosis and Angiogenesis of Periodontal Ligament Stem Cells via the Akt/ERK1/2/BAD Signaling Pathway under Inflammatory Microenvironment 