[Retracted] lncRNA HOTTIP Recruits EZH2 to Inhibit PTEN Expression and Participates in IM Resistance in Chronic Myeloid Leukemia

Figure 6

HOTTIP work through EZH2 to participate in drug resistance. Note: (a) IR-K562 cells were transfected with specific sh-HOTTIP or both sh-HOTTIP+sh-EZH2. The CCK-8 analysis was used to detect cell proliferation. (b) Cell apoptosis was detected by flow cytometry using Annexin V/APC/PI. The right panel shows the apoptosis rate from three independent experiments. (c) IR-K562 cells were prepared with different Imatinib concentrations for 48 h. The CCK-8 analysis was used to detect cell inhibition. (d) WB was used to detect protein levels.

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