Donor Mesenchymal Stem Cells Program Bone Marrow, Altering Macrophages, and Suppressing Endometriosis in Mice

Figure 2

Endometriosis was not affected by direct MSC administration. (a) Schematic diagram showing timeline for MSC or vehicle administration and tissue collection from endometriosis mice (N = 8). MSCs were injected retro-orbitally on Day 0 and 30 after grafting uterine fragments into the peritoneal cavity. (b) Images showing lesions formation in mice administered PBS or MSCs (N = 8 each group). No significant differences were noted. (c) Lesion volume was assessed on Day 60. Results are expressed as mean SEM of total volume of lesions in mm³ ().

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