Review Article
Promising Markers in the Context of Mesenchymal Stem/Stromal Cells Subpopulations with Unique Properties
Table 3
Expression of markers for more specialized subpopulations in different MSC sources.
| Marker | MSC source | % of cells | Comments | Reference |
| CD142 | WJ (explant) | 71.2–88 | Depending on donors | [109] |
| CD146 | AT | 5 | | [29] |
| CD146 | AT | ∼5 | | [29] |
| CD146 | AT | ∼18.9 | Semiconfluent culture | [110] |
| CD146 | BM | ∼5 | | [29] |
| CD146 | BM | 50.1 | | [111] |
| CD146 | DM | 22 | | [33] |
| CD146 | DP | 38.8 | | [112] |
| CD146 | WJ | 21.8 | | [29] |
| CD200 | AT | (1) 24% (2) 80% | (1) Subcutaneous fat derived cells (2) Visceral fat derived cells | [113] |
| CD200 | BM | 23–63.4 | The highest level of CD200 at the density 30 × 103 cells/cm2 | [114] |
| CD200 | PL | (1) ∼70 (2) ∼1.8 | Passage 5, (1) fetal PL, (2) maternal PL | [115] |
| CD317 | BM | 1–3 | | [116] |
| CD317 | BM | (1) 28 (2) 1.7 | Two distinct subpopulations: CD317dim (1) and CD317bright (2) | [117] |
| Nestin | Kidney | 1.1 | Nestin-GFP mice | [118] |
| Nestin | Spleen | 0.7 | Nestin-GFP mice | [119] |
| VCAM | AT | 0.73 | Passage 3 | [120] |
| VCAM | BM | 32.04 | Passage 3 | [120] |
| VCAM | CV | 65.01 | Passage 3 | [120] |
| VCAM | CV | 62.9 | | [121] |
| VCAM | UC | 7.44 | Passage 3 | [120] |
| VCAM | UC | 88 | After proinflammatory induction | [122] |
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Note: ∼: approximately, AT: adipose tissue, BM: bone marrow, CV: chorionic villi, GFP: Green Fluorescence Protein, PL: placenta, UC: umbilical cord, WJ: Wharton Jelly. Source of MSCs: human, unless otherwise stated.
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