Review Article

Promising Markers in the Context of Mesenchymal Stem/Stromal Cells Subpopulations with Unique Properties

Table 3

Expression of markers for more specialized subpopulations in different MSC sources.

MarkerMSC source% of cellsCommentsReference

CD142WJ (explant)71.2–88Depending on donors[109]

CD146AT5[29]

CD146AT∼5[29]

CD146AT∼18.9Semiconfluent culture[110]

CD146BM∼5[29]

CD146BM50.1[111]

CD146DM22[33]

CD146DP38.8[112]

CD146WJ21.8[29]

CD200AT(1) 24%
(2) 80%
(1) Subcutaneous fat derived cells
(2) Visceral fat derived cells
[113]

CD200BM23–63.4The highest level of CD200 at the density 30 × 103 cells/cm2[114]

CD200PL(1) ∼70
(2) ∼1.8
Passage 5, (1) fetal PL,
(2) maternal PL
[115]

CD317BM1–3[116]

CD317BM(1) 28
(2) 1.7
Two distinct subpopulations: CD317dim (1) and CD317bright (2)[117]

NestinKidney1.1Nestin-GFP mice[118]

NestinSpleen0.7Nestin-GFP mice[119]

VCAMAT0.73Passage 3[120]

VCAMBM32.04Passage 3[120]

VCAMCV65.01Passage 3[120]

VCAMCV62.9[121]

VCAMUC7.44Passage 3[120]

VCAMUC88After proinflammatory induction[122]

Note: ∼: approximately, AT: adipose tissue, BM: bone marrow, CV: chorionic villi, GFP: Green Fluorescence Protein, PL: placenta, UC: umbilical cord, WJ: Wharton Jelly. Source of MSCs: human, unless otherwise stated.