Research Article

MMP9-Associated Tumor Stem Cells, CCL1-Silenced Dendritic Cells, and Cytokine-Induced Killer Cells Have a Remarkable Therapeutic Efficacy for Acute Myeloid Leukemia by Activating T Cells

Table 1

Clinical Characteristics of AML Patients.

CharacteristicsMedian (range)No. of cases

Sex
Female4
Male8
Total12
Age
Median (years)56.5 (27-76)
WBC
Median (×109/L)15.15 (1.25-221.0)
Platelets
Median (×109/L)71.5 (13.0-247.0)
AML FAB subtype
AML with maturation: M27
Acute monoblastic or monocytic leukemia: M55
Karyotype
Normal6
Medium2
Complex2
Unknown2
Gene mutations
NPM14
FLT3-ITD4
TP532
RUNX11
CEBPA1

Abbreviations: AML: acute myeloid leukemia; WBC: white blood cell; FAB subtype: French-American-British subtype; NPM1: nucleophosmin 1; FLT3-ITD: FLT3 internal tandem duplication; TP53: tumor protein p53; RUNX1: runt-related transcription factor 1; CEBPA: CCAAT enhancer binding protein alpha.