A Novel Molecular Classification Method for Glioblastoma Based on Tumor Cell Differentiation Trajectories

Figure 5

Classification of GBM samples from TCGA and CGGA datasets based on the expression profiles of the five clusters of malignant cells. (a) Venn diagram showing the similarities and differences of the calculated markers of Ac-G/Class-G/Neo-G/Opc-G/Undiff-G clusters. (b) Heatmap showing the expressions of the selected 64 marker genes of Ac-G/Class-G/Neo-G/Opc-G/Undiff-G in all 13 clusters. (c, d) Heatmap showing the abundance of the 5 clusters in the five clustered groups of TCGA and CGGA samples. (e, f) The Kaplan-Meier curves of OS for the five clustered groups of TCGA and CGGA patients.

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