Research Article

hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts

Figure 3

hucMSC-Ex inhibits the expression of α-SMA, TGF-β, collagen I, collagen III, and fibronectin in mouse colons. (a) Western blot analysis of α-SMA, TGF-β, collagen I, collagen III, and fibronectin expression in mouse colon. (b) QRT-PCR analysis of TGF-β, α-SMA, COL1A1, COL3A1, and FN1 expression in mouse colon tissue ( and ). (c) The expression levels of fibronectin and α-SMA in mouse colon tissue as detected by IHC (200x).
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