Research Article

AT7867 Inhibits the Growth of Colorectal Cancer Stem-Like Cells and Stemness by Regulating the Stem Cell Maintenance Factor Ascl2 and Akt Signaling

Table 1

Tumor formation of HCT116 fifth-passage sphere cells and parental cells.

Cell types104 cells105 cells

HCT116 5th spheres cells2/44/4
HCT116 parental cells0/41/4

Note: equal numbers (104 and 105) of HCT116 5th-passage sphere cells and HCT116 parental cells were implanted simultaneously in the left and right sides of nude mice, respectively. Tumor formation rate was calculated after 4 weeks.