Review Article

Comparison of Biological Properties and Clinical Application of Mesenchymal Stem Cells from the Mesoderm and Ectoderm

Table 3

The function of E-MSCs in mediating immune cells.

Immune cell typeE-MSC functions

PBMCsInhibiting PBMC proliferation
DCsInhibiting DC differentiation and maturation
MacrophageActivating M2 macrophage polarization in general; activating M1 macrophage polarization in specific microenvironment
Mast cellsInhibiting mast cell exocytosis
T cellInhibiting T cell proliferation, differentiation, and apoptosis
B cellInhibiting B cell exocytosis

Abbreviation: PBMCs: peripheral blood mononuclear cells; DCs: dendritic cells.