Inhibition of Autophagy Maintains ESC Pluripotency and Inhibits Primordial Germ Cell Formation in Chickens

Figure 3

Enrichment analysis of DEGs in ESCs and PGCs in chicken. (a) Volcano map of DEGs between ESCs and PGCs. The red dots represent significantly upregulated genes in PGCs; the green dots represent significantly downregulated genes. Genes that are not differentially expressed are shown in gray. (b) Heat map showing DEGs between ESCs and PGCs. Blue represents weakly expressed genes, and red represents highly expressed genes. (c) KEGG enrichment analysis of the DEGs. (d) Expression comparisons of autophagy genes detected by RNA-seq and qRT-PCR between ESCs and PGCs.

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