Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts

<div>Endocytic hucMSC-EMVs in MC 3 T 3-E1 cells. EMVs were not endocytosed into the cytoplasm at 0 hr, but they were endocytosed into the cytoplasm at 12, 24, and 48 hr, and EMV endocytosis increased significantly over time, increasing aggregation along the nuclear membrane at 24 and 48 hr (scale bar: 50 <i>μ</i>m).</div>

Stem Cells International

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Figure 4: Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts 

Figure 4 | Human Mesenchymal Stem Cells-Derived Exosome Mimetic Vesicles Regulation of the MAPK Pathway and ROS Levels Inhibits Glucocorticoid-Induced Apoptosis in Osteoblasts 