Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/<i>β</i>-Catenin Pathway

<div>ADSC-Exos increased skin thickness and the number of hair follicles, and accelerated telogen-to-anagen transition. (a) The 7-week-old C57/BL6 mice were randomly divided into control, DHT, Minoxidil, Exos, DHT + Exos and DHT + Minoxidil groups for treatment after dorsal depilation. The observation period was 21 days, and pictures were taken on days 0, 6, 12, 18 and 21, 6 in each group. (b) HE staining of dorsal skin of mice in each group. Longitudinal section of skin, scale bar: 200 <i>μ</i>m. (c) HE staining of dorsal skin of mice in each group. Transverse section of skin, scale bar: 200 <i>μ</i>m. (d) Quantitative comparison of skin thickness in each group of mice. 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Stem Cells International

fig5

Figure 5

Figure 5: Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/<i>β</i>-Catenin Pathway 

Figure 5 | Adipose-Derived Stem Cell Exosomes Antagonize the Inhibitory Effect of Dihydrotestosterone on Hair Follicle Growth by Activating Wnt/β-Catenin Pathway 