Galectin-3 Plays an Important Role in BMP7-Induced Cementoblastic Differentiation of Human Periodontal Ligament Cells by Interacting with Extracellular Components

Figure 5

Ectopic expression of galectin-3 inhibits fibroblastic activation and induces cementoblastic differentiation. Ectopic expression of full-length cDNA of galectin-3 in hPDLCs was performed as indicated in Materials and Methods. The changes of protein amounts and cellular morphologies are shown in (a, b), respectively. 1, vector only; 2, cDNA transfection. (c) Transcriptional expression of the representative cementoblastic (a–c) and fibroblastic (d, e) markers. ; ; . Statistical analysis was performed using Student’s -test ().

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