Fabrication of ECM Mimicking Bioactive Scaffold: A Regenerative Approach for MSC Mediated Applications

<div>(a) <i>Aloe vera</i> with 10% gelatin (AV/G) freeze-dried scaffold. (b) Gingival tissue collected from human dental tooth pulp. (c) Phase contrast images of MSCs at <svg height="8.69875pt" id="M17" style="vertical-align:-0.3499298pt" version="1.1" viewbox="-0.0498162 -8.34882 20.286 8.69875" width="20.286pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g><g transform="matrix(.013,0,0,-0.013,6.24,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,12.48,0)"><path d="M528 54L331 254L528 455L492 493L294 291L96 493L60 455L257 254L60 54L96 16L294 217L492 16L528 54Z"></path></g></svg> magnification. Human mesenchymal stem cells isolated from gingival tissue. (d) Red oil droplets represent adipogenic differentiation by oil red O staining. (e) Pink colour stain shows phosphate deposition in the nucleus, representing osteogenic differentiation by an alkaline phosphatase.</div>

Stem Cells International

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Figure 1

Figure 1: Fabrication of ECM Mimicking Bioactive Scaffold: A Regenerative Approach for MSC Mediated Applications 